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[肿瘤细胞超微结构]

[Tumor cell ultrastructure].

作者信息

Iagubov A S, Kats V A

出版信息

Vopr Onkol. 1976;22(3):64-7.

PMID:820072
Abstract

The ultrastructure of tumor cells, as compared with normal ones, was studied morphometrically. It was found that the relationship between the ergastoplasmic apparatus and polyribosomal one could serve as an objective criterion of the degree of differentiation of normal cells under study. Tumor cells did not differ from normal cells with regard to one system of organells being more highly developed than the other, but they did from the point of view of different relations between the protein-synthesizing and energetic apparatuses. Also, tumor cells were found to be less differentiated than normal, and more malignant tumors show no less differentiation than more benign ones. Tumor cells are likely to have their own trends of development that differ from the processes of normal cells differentiation.

摘要

对肿瘤细胞与正常细胞的超微结构进行了形态计量学研究。发现内质网结构与多核糖体结构之间的关系可作为所研究正常细胞分化程度的客观标准。在一个细胞器系统比另一个更发达方面,肿瘤细胞与正常细胞并无差异,但从蛋白质合成和能量供应结构之间的不同关系来看则有差异。此外,发现肿瘤细胞的分化程度低于正常细胞,而且恶性程度较高的肿瘤并不比良性程度较高的肿瘤分化程度低。肿瘤细胞可能有其自身不同于正常细胞分化过程的发育趋势。

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