Ojha M, Cobbold R S, Johnston K W
Institute of Biomedical Engineering, University of Toronto, Ontario, Canada.
J Vasc Surg. 1994 Jun;19(6):1067-73. doi: 10.1016/s0741-5214(94)70219-5.
The purpose of this article was to study the effects of anastomotic angle on the wall shear stress distribution for end-to-side anastomosis models under pulsatile flow conditions.
The photochromic tracer technique was used to visualize the flow field and to determine the instantaneous wall shear stress at multiple locations simultaneously. Models with angles of 20, 30, 45, and 60 degrees were examined.
For all angles, low shear stress was present at the heel and on the bed opposite the heel of the anastomosis apparently as a result of the complete occlusion of the proximal end of the host vessel. Near the toe, increased flow separation occurred with increasing angle. On the bed across from the toe, increasing the angle led to increased shear stress. In addition, in this region the anastomotic angle significantly altered other properties of the shear stress field such as the mean and peak-to-peak magnitudes and cycle-to-cycle fluctuations.
This study provides quantitative data on the wall shear stress distribution within an end-to-side anastomosis and its relation to the anastomotic angle. The results are discussed in terms of possible roles of shear-induced intimal hyperplasia.
本文旨在研究脉动流条件下，端侧吻合模型中吻合角度对壁面剪应力分布的影响。
采用光致变色示踪技术可视化流场，并同时测定多个位置的瞬时壁面剪应力。研究了角度分别为20度、30度、45度和60度的模型。
对于所有角度，吻合口足跟处及足跟对侧的床面出现低剪应力，这显然是由于宿主血管近端完全闭塞所致。在趾部附近，随着角度增加，流动分离增加。在趾部对面的床面上，增大角度会导致剪应力增加。此外，在该区域，吻合角度显著改变了剪应力场的其他特性，如均值、峰峰值大小和逐周期波动。
本研究提供了端侧吻合内壁面剪应力分布及其与吻合角度关系的定量数据。从剪切诱导内膜增生的可能作用方面对结果进行了讨论。
