Yoshioka M, Ishii T, Fukunishi I
Department of Psychiatry, Sagamidai Hospital, Sagami, Japan.
Jpn J Psychiatry Neurol. 1993 Dec;47(4):847-51. doi: 10.1111/j.1440-1819.1993.tb01832.x.
Sleep disturbance of patients with end-stage renal disease was examined in a sample of 127 patients receiving hemodialysis (HD) therapy. The results indicate that sleep disturbance occurs quite often. Especially, there was a high incidence of sleep disturbance with prolonged HD therapy and with advancing age, and that somatic complications due to long-term HD indirectly influence sleep disturbance. On the effect of drug therapy, levodopa produced significant clinical effects on RLS compared to ordinary hypnotics. Carbamazepine equally tended to produce favorable clinical effects on RLS.
在127例接受血液透析（HD）治疗的患者样本中，对终末期肾病患者的睡眠障碍进行了检查。结果表明，睡眠障碍相当常见。特别是，随着HD治疗时间延长和年龄增长，睡眠障碍的发生率较高，并且长期HD引起的躯体并发症间接影响睡眠障碍。关于药物治疗的效果，与普通催眠药相比，左旋多巴对不宁腿综合征产生了显著的临床效果。卡马西平同样倾向于对不宁腿综合征产生良好的临床效果。
