Stratford C J, Owen B M
Medical School, University of Newcastle, Newcastle upon Tyne.
Lepr Rev. 1994 Mar;65(1):58-65. doi: 10.5935/0305-7518.19940005.
The aim of this study was to identify the effect of footwear on sensory testing in leprosy. This was achieved by using 3 methods of sensory testing within 1 district of East Africa. We included 72 leprosy patients and 36 patients (nonleprosy patients) in the study and these were subdivided into 2 groups, depending on whether they normally wore shoes or went barefoot. The methods used were the WHO sensory test, graded monofilaments and the biothesiometer. The results showed significant differences in the threshold levels between both groups of patients with the biothesiometer and monofilaments, demonstrating the importance of having separate values when screening for leprosy and assessing which patients are at the most risk of developing ulcers. The importance of having quantitative methods of testing was also demonstrated, as only then can the results be sufficiently standardized to identify the at-risk groups and also be sufficiently sensitive to differentiate between shoe wearing and nonshoe wearing patients.
本研究的目的是确定鞋类对麻风病感觉测试的影响。这是通过在东非的一个地区使用3种感觉测试方法来实现的。我们纳入了72名麻风病患者和36名患者（非麻风病患者）进行研究，根据他们平时是穿鞋还是赤脚将这些患者分为2组。所使用的方法是世界卫生组织感觉测试、分级单丝和生物感觉测定仪。结果显示，使用生物感觉测定仪和单丝时，两组患者的阈值水平存在显著差异，这表明在筛查麻风病和评估哪些患者发生溃疡的风险最高时，有单独的数值很重要。还证明了采用定量测试方法的重要性，因为只有这样，结果才能充分标准化以识别高危人群，并且足够敏感以区分穿鞋和不穿鞋的患者。
