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秀丽隐杆线虫中类水手重复序列的鉴定。

Identification of a mariner-like repetitive sequence in C. elegans.

作者信息

Sedensky M M, Hudson S J, Everson B, Morgan P G

机构信息

Department of Anesthesiology, Case Western Reserve University, Cleveland, OH.

出版信息

Nucleic Acids Res. 1994 May 11;22(9):1719-23. doi: 10.1093/nar/22.9.1719.

Abstract

A repetitive element in C.elegans has been found that bears high homology to the element mariner of Drosophila mauritiana (EMBL accession number X77804). This element is present in about 20 copies in the N2 strain of C.elegans, and appears in roughly equal copy numbers in the related strain BO and in the hybrid strains RW7097 and TR679. There is only one copy of this MLE in three related species of Caenorhabditis. A cDNA of this mariner-like element (MLE) codes for a protein with 58% homology to the Drosophila transposase. The mariner-like element is not mobile in N2. This class of elements has now been described in insects, planaria and nematodes (GenBank accession number M98552 and this report).

摘要

在秀丽隐杆线虫中发现了一种重复元件,它与毛里求斯果蝇的mariner元件具有高度同源性(EMBL登录号X77804)。该元件在秀丽隐杆线虫的N2品系中约有20个拷贝,在相关品系BO以及杂交品系RW7097和TR679中的拷贝数大致相等。在秀丽隐杆线虫的三个相关物种中,这种MLE只有一个拷贝。这种类mariner元件(MLE)的cDNA编码一种与果蝇转座酶具有58%同源性的蛋白质。类mariner元件在N2中不具有移动性。现在已经在昆虫、涡虫和线虫中描述了这类元件(GenBank登录号M98552及本报告)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e87/308055/e57ed035c66e/nar00033-0218-a.jpg

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