Meyer B, Weilenmann R
CIBA-GEIGY AG, Departement Forschung und Entwicklung, Basel.
Schweiz Arch Tierheilkd. 1994;136(4):150-3.
First we describe the application of an injection anaesthesia in a specific strain of rats and test its usefulness under practical conditions. Application (i.p.) of the described dose according to the animals body-weight resulted in an acceptable anaesthesia, which lasted approximately 50 minutes in male rats and 80 minutes in female rats. Next we compare the common ether anaesthesia with an other inhalation anaesthesia (Methoxyflurane) which, by using a self-made mask, could be prolonged without any problem for at least 15 minutes ("prolonging-time"). A correlation was found between the duration of the prolonging-time and the awakening time. Inhalation anaesthesia using Methoxyflurane obviously affected the animals health and well-being less than the conventional ether anaesthesia.
首先，我们描述了一种注射麻醉剂在特定品系大鼠中的应用，并在实际条件下测试其效用。根据动物体重腹腔注射所述剂量可产生可接受的麻醉效果，雄性大鼠的麻醉持续约50分钟，雌性大鼠约80分钟。接下来，我们将常用的乙醚麻醉与另一种吸入麻醉（甲氧氟烷）进行比较，通过自制面罩，后者的麻醉时间可毫无问题地延长至少15分钟（“延长时间”）。延长时间与苏醒时间之间存在相关性。使用甲氧氟烷的吸入麻醉对动物健康和状态的影响明显小于传统的乙醚麻醉。
