Rosenberg F R, Sanders S, Nelson C T
Arch Dermatol. 1976 Jul;112(7):962-70. doi: 10.1001/archderm.112.7.962.
We review 107 consecutive cases of pemphigus. The mortality for pemphigus vulgaris and pemphigus vegetans was 46% between 1949 and 1959 and 24% between 1960 and 1970. The overall mortality for all types of pemphigus was 32%. In the corticosteroid era, complications of therapy were the most frequent causes of death. Mortality and morbidity closely correlated with the corticosteroid dosage used to attain control. This dosage proved to be variable and could not be predicted at the outset in any given patient.
我们回顾了107例连续性天疱疮病例。寻常型天疱疮和增殖型天疱疮在1949年至1959年间的死亡率为46%，在1960年至1970年间为24%。所有类型天疱疮的总体死亡率为32%。在皮质类固醇时代，治疗并发症是最常见的死亡原因。死亡率和发病率与为达到控制而使用的皮质类固醇剂量密切相关。事实证明，该剂量因人而异，在任何特定患者一开始都无法预测。
