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溃疡性结肠炎和肠易激综合征患者乳糖酶水解障碍

[Disorders of lactase hydrolysis in patients with ulcerous colitis and irritable colon].

作者信息

Aleksić D

机构信息

Zavod za zastitu zdravlja Srbije, Beograd.

出版信息

Srp Arh Celok Lek. 1993 Jan-Feb;121(1-2):1-3.

PMID:8202812
Abstract

In 28 patients the existence of deficiency in lactase activity was examined indirectly with lactose tolerance test (LTT). Patients were divided in three groups. The first group consisted of 12 patients with confirmed diagnosis of "Irritable-colon syndrome". The second was composed of 6 patients suffering from ulcerative colitis. The third examined group was control group made of healthy persons without any gastrointestinal or metabolic disorders. To exclude the possible of monosaccharide malabsorption, all patients underwent glucose-tolerance test (GTT). Milk tolerance questionnaire was performed in all examined patients. All clinical signs were observed for 12 hours after performing LTT. Following the statistical analysis it was found that there was greater frequency of lactose intolerance in two first groups (I and II), comparing with the results obtained in the control group. Low raise of glucose level (less than 1.11 mmol/l) in the majority of patients was connected with characteristic lactose-intolerance clinical signs and symptoms.

摘要

对28例患者采用乳糖耐量试验(LTT)间接检测乳糖酶活性缺乏情况。患者分为三组。第一组由12例确诊为“肠易激综合征”的患者组成。第二组由6例溃疡性结肠炎患者组成。第三组为对照组,由无任何胃肠道或代谢紊乱的健康人组成。为排除单糖吸收不良的可能性,所有患者均接受了葡萄糖耐量试验(GTT)。对所有受检患者进行了牛奶耐受问卷调查。在进行LTT后12小时观察所有临床症状。经过统计分析发现,与对照组结果相比,前两组(I组和II组)乳糖不耐受的发生率更高。大多数患者血糖水平升高幅度低(低于1.11 mmol/l)与典型的乳糖不耐受临床症状和体征相关。

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