Shoĭkhet Ia N, Ogloblina O G, Tseĭmakh E A, Mal'chenko T D
Ter Arkh. 1994;66(3):64-7.
Prevailing fibrin-formation in the pleural cavity entails hypoactivity of trypsin-like proteinases and a high inhibitory potential in the serum and pleural exudate. Streptokinase preparations appeared an effective means of pharmacological pulmonary decortication in patients with high pleural levels of plasminogen. The authors obtained higher efficacy of conservative therapy for pyothorax when they used a specially designed technique of intrapleural administration of streptokinase-activated fresh frozen plasma of the same group. The outcomes of the disease were also improved noticeably.
胸腔内纤维蛋白形成占主导时，会导致类胰蛋白酶活性降低以及血清和胸腔渗出液中具有较高的抑制潜能。链激酶制剂似乎是纤溶酶原胸腔高水平患者进行药物性肺剥脱术的有效手段。作者采用同一组经链激酶激活的新鲜冷冻血浆胸膜腔内给药的特殊设计技术时，脓胸保守治疗取得了更高疗效。疾病的预后也有明显改善。
