Simonin P, Niederhauser H U, Duchosal P W
Arch Mal Coeur Vaiss. 1976 Apr;69(4):341-8.
His bundle recording combined with atrial pacing permit to evaluate atrio-ventricular conduction and the function of the sinus node by measuring the corrected sinus recovering time (CSRT). Three groups of 10 patients are included in this study: -- Group I is composed of control patients; the CSRT varies between 30 and 450 msec (mean value : 320 msec +/- 123.3). Neither atrio-ventricular nor intraventricular block was observed during His bundle recording combined with atrial pacing. -- Group II, composed of patients with atrial dysrhythmia has a CSRT varying from 720 to 5.900 msec (mean value: 2.750 msec +/- 184.5). Six of these patients have atrio-ventricular conduction disturbances. -- In group III all patients had atrio-ventricular or intraventricular conduction defects without atrial dysrhythmia. CSRT varies between 205 and 510 msec (mean value: 310 +/- 88.6). The authors conclude that atrial dysrhythmia is probably an original degenerative disease which is different from the "Lenègre" disease, by his incidence, the location of the lesions and the clinical issue. This conclusion is made by comparing the results of the authors with the analysis by James of the embryogenesis of the sinus node and of atrial and atrio-ventricular pathways.
希氏束记录结合心房起搏可通过测量校正窦房结恢复时间（CSRT）来评估房室传导和窦房结功能。本研究纳入三组患者，每组10例：——第一组为对照患者；CSRT在30至450毫秒之间变化（平均值：320毫秒±123.3）。在希氏束记录结合心房起搏过程中未观察到房室或室内传导阻滞。——第二组由房性心律失常患者组成，CSRT在720至5900毫秒之间变化（平均值：2750毫秒±184.5）。其中6例患者存在房室传导障碍。——第三组所有患者均有房室或室内传导缺陷，但无房性心律失常。CSRT在205至510毫秒之间变化（平均值：310±88.6）。作者得出结论，房性心律失常可能是一种原发性退行性疾病，在发病率、病变部位和临床问题方面与“勒内格”病不同。该结论是通过将作者的结果与詹姆斯对窦房结以及心房和房室传导通路胚胎发生的分析结果进行比较得出的。
