Rayment I, Holden H M
Department of Biochemistry, Institute for Enzyme Research, Madison, WI 53705.
Trends Biochem Sci. 1994 Mar;19(3):129-34. doi: 10.1016/0968-0004(94)90206-2.
Myosin is one of only three proteins known to convert chemical energy into mechanical work. Although the chemical, kinetic and physiological characteristics of this protein have been studied extensively, it has been difficult to define its molecular basis of movement. With the recent X-ray structural determination of the myosin head, however, it is now possible to put forward a hypothesis on how myosin might function as a molecular motor.
肌球蛋白是已知的仅有的三种能将化学能转化为机械功的蛋白质之一。尽管对这种蛋白质的化学、动力学和生理学特性已进行了广泛研究，但一直难以确定其运动的分子基础。然而，随着最近肌球蛋白头部的X射线结构测定，现在有可能提出一个关于肌球蛋白如何作为分子马达发挥作用的假说。
