大鼠中DMBA诱导的乳腺肿瘤和Walker癌肉瘤对32P摄取的昼夜变化。
Circadian variations in 32P uptake of DMBA-induced mammary tumour and Walker carcinosarcoma in rats.
作者信息
Møoller U, Bojsen J
出版信息
Br J Cancer. 1976 Jun;33(6):646-54. doi: 10.1038/bjc.1976.102.
Abstract
The 32P uptake in a mammary tumour induced by DMBA and in the Walker 256 carcinosarcoma was measured by external GM -tubes. The uptake was significantly higher than in the skin. During exposure to a synchronized light regime a circadian variation was present in the 32P uptake of the hormone-dependent DMBA-induced tumour. The maximal 32P uptake was in the dark period, in which the highest temperature in the tumour has also been found (Møoller and Bojsen, 1975). In the hormone-independent Walker 256 carcinosarcoma there was no periodicity in 32P uptake. No variation in 32P uptake was registered in the skin of normal controls or in tumour-bearing rats.
摘要
通过外部盖革-弥勒计数管测量了二甲基苯并蒽（DMBA）诱导的乳腺肿瘤和沃克256癌肉瘤中32P的摄取情况。其摄取量显著高于皮肤中的摄取量。在同步光照条件下，激素依赖性DMBA诱导肿瘤的32P摄取存在昼夜变化。32P摄取最大值出现在黑暗期，而肿瘤中最高温度也出现在该时期（Møoller和Bojsen，1975年）。在激素非依赖性沃克256癌肉瘤中，32P摄取没有周期性。正常对照大鼠或荷瘤大鼠的皮肤中未记录到32P摄取的变化。
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本文引用的文献
1
Twenty-four hour rhythm in the mitotic activity of normal mammary epithelium on normal and inverted lighting regimens.正常光照和倒置光照方案下正常乳腺上皮有丝分裂活动的24小时节律。
J Physiol. 1963 Mar;165(3):437-42. doi: 10.1113/jphysiol.1963.sp007068.
2
Further studies on mammary tumours induced in rats by 7,12-dimethylbenz(A)anthracene (DMBA).关于7,12-二甲基苯并(a)蒽（DMBA）诱导大鼠乳腺肿瘤的进一步研究。
Int J Cancer. 1967 Mar 15;2(2):163-77. doi: 10.1002/ijc.2910020211.
3
The continuous counting of phosphorus-32 from transplanted rat tumours and the effects of radiosensitisers and radioprotective agents.对移植大鼠肿瘤中磷-32的连续计数以及放射增敏剂和放射防护剂的作用。
Br J Cancer. 1967 Jun;21(2):438-47. doi: 10.1038/bjc.1967.50.
4
Effects of progesterone on 9,10-dimethyl-1,2-benzanthracene-induced mammary tumours in Sprague-Dawley rats.孕酮对斯普拉格-道利大鼠9,10-二甲基-1,2-苯并蒽诱导的乳腺肿瘤的影响。
Br J Cancer. 1967 Jun;21(2):418-29. doi: 10.1038/bjc.1967.48.
5
Effects of x-irradiation on parameters of tumor growth, histology, and ultrastructure.X射线辐射对肿瘤生长参数、组织学及超微结构的影响。
Cancer. 1969 Jul;24(1):39-55. doi: 10.1002/1097-0142(196907)24:1<39::aid-cncr2820240105>3.0.co;2-v.
6
7
Changes in 32P counting-rate in human and animal tumours.
Br J Radiol. 1968 Jun;41(486):440-7. doi: 10.1259/0007-1285-41-486-440.
8
An interpretation of the results of measurements of the uptake of 32P in human tumours.
Br J Radiol. 1968 Jun;41(486):432-9. doi: 10.1259/0007-1285-41-486-432.
9
[Strength of a light-dark cycle as a time determiner for circadian rhythm in man].[明暗周期作为人类昼夜节律时间决定因素的强度]
Pflugers Arch. 1970;321(2):133-42. doi: 10.1007/BF00586368.
10
Radiotelemetrical equipment for continuous subcutaneous measurements of the circadian temperature rhythm in rats.用于连续皮下测量大鼠昼夜体温节律的无线电遥测设备。
Pflugers Arch. 1971;328(2):176-84. doi: 10.1007/BF00592445.
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