Batsakis J G, Cleary K R, Cho K J
Department of Pathology, University of Texas M. D. Anderson Cancer Center, Houston 77030.
Ann Otol Rhinol Laryngol. 1994 Jun;103(6):495-7. doi: 10.1177/000348949410300613.
Lichen planus is a mucocutaneous disease of unknown cause that has its principal clinical manifestations in the skin and mucosa of the oral cavity. The natural history of the cutaneous form is one of spontaneous resolution over time, while oral lichen planus pursues a much more chronic course with a low order of resolution. Oral lichen planus must be distinguished from lichenoid lesions, including lichenoid dysplasia. Malignant change in oral lichen planus is rare and is prompted by carcinogenic cofactors. There is no increased risk of development of carcinoma in cutaneous lichen planus.
扁平苔藓是一种病因不明的黏膜皮肤疾病,其主要临床表现见于皮肤和口腔黏膜。皮肤型扁平苔藓的自然病程是随时间自发消退,而口腔扁平苔藓病程更为慢性,消退率较低。口腔扁平苔藓必须与苔藓样病变(包括苔藓样发育异常)相鉴别。口腔扁平苔藓发生恶变罕见,是由致癌辅助因素诱发的。皮肤扁平苔藓不存在发生癌变风险增加的情况。