Hoppe J E, Klingebiel T, Niethammer D
Department of Pediatric Hematology and Oncology, University Children's Hospital, Tübingen, Germany.
Pediatr Hematol Oncol. 1994 Mar-Apr;11(2):207-10. doi: 10.3109/08880019409141658.
We observed an alarmingly high rate (5/16 patients; 31.3%) of orointestinal colonization with Candida glabrata--often in high numbers--in pediatric bone marrow transplant recipients receiving fluconazole as antifungal prophylaxis. This selection is probably due to the intrinsically low susceptibility of C. glabrata to fluconazole.
