Pucheu A, Leduc B, Sillet-Bach I, Payen C, Pucheu M E
Service d'oncologie, CHG, Brive, France.
Bull Cancer. 1993 Aug;80(8):680-8.
Seventy-two consecutive patients with totally implanted catheters for administration of chemotherapy for solid tumours or lymphomas were studied prospectively to assess the prevalence of venous thrombosis. During the follow-up period of 343 (6-1,177) days, 11 cases of venous thrombosis (15.2%), of which 45% were partial and only 36% symptomatic were observed. Venous thrombosis was an early complication, 6/11 cases being observed within 1 month of implantation. No clinical or biological predisposing factor, apart from the presence of malignant disease, could be identified. Doppler ultrasonography is a good method of following-up these patients. This method should become an essential diagnostic tool in this field.
对72例连续使用完全植入式导管进行实体瘤或淋巴瘤化疗的患者进行前瞻性研究,以评估静脉血栓形成的发生率。在343(6 - 1177)天的随访期内,观察到11例静脉血栓形成(15.2%),其中45%为部分血栓形成,仅有36%有症状。静脉血栓形成是一种早期并发症,11例中有6例在植入后1个月内观察到。除了存在恶性疾病外,未发现其他临床或生物学诱发因素。多普勒超声检查是随访这些患者的一种好方法。该方法应成为该领域必不可少的诊断工具。