Burt C T, Ribolow H
MRI Center, University of Illinois at Chicago 60612-7336.
Comp Biochem Physiol Biochem Mol Biol. 1994 May;108(1):11-20. doi: 10.1016/0305-0491(94)90158-9.
Water-soluble phosphodiesters (WSPDE) are a prominent feature of many 31P-NMR spectra; however, their role has remained somewhat of a mystery. What has been missed in almost all previous studies is the fact that two classes of WSPDE exist in vertebrates: those in mammals and those in the other (reptile-avian) line. The first is represented by glycerol phosphorylcholine and the second by serine ethanolamine phosphodiester. A further examination of the literature suggests a common role for all WSPDE as lysophospholipase inhibitors and therefore net sparers of phospholipids by decreasing phospholipid metabolic throughput.
