Waxman M
Cancer. 1976 Sep;38(3):1452-6. doi: 10.1002/1097-0142(197609)38:3<1452::aid-cncr2820380353>3.0.co;2-c.
A case of a malignant undifferentiated germ cell tumor in situ of an undescended testis diagnosed by needle biopsy is described. Four similar cases have been so far recorded in the literature, all of them in the infertile men with normally descended descended testes. Two of them developed embryonal carcinoma of testis 4 1/2 later and one had a concomitant seminoma. In a high-risk group of patients (atrophic testis, cryptorchidism), a needle biopsy of a testicle may discover malignancy in its very early phase of development (Stage 0), at which time an orchiectomy alone may be a curative treatment.
本文描述了一例通过针吸活检诊断为未降睾丸原位恶性未分化生殖细胞肿瘤的病例。迄今为止，文献中已记录了4例类似病例，所有病例均为睾丸正常下降的不育男性。其中2例在4年半后发生睾丸胚胎癌，1例同时伴有精原细胞瘤。在高危患者组（萎缩性睾丸、隐睾症）中，睾丸针吸活检可能在肿瘤发展的极早期阶段（0期）发现恶性肿瘤，此时单独进行睾丸切除术可能是一种治愈性治疗方法。
