Dorman S, Trainer T D, Lefke D, Leadbetter G
Cancer. 1979 Oct;44(4):1357-62. doi: 10.1002/1097-0142(197910)44:4<1357::aid-cncr2820440429>3.0.co;2-a.
A 13-year-old male who had bilateral cryptorchid testes since birth underwent testicular biopsies and subsequent left orchiectomy following a diagnosis of malignant germ cell tumor. No tumor mass was noted although the malignant cells were seen within the seminiferous tubules and the interstitium. Five recorded cases of in-situ or incipient germ cell neoplasms of the testes are reviewed; three were infertile, another had a cryptorchid testis, and the fifth was both infertile and cryptorchid. Two of these patients have developed frank carcinoma, which would suggest that the process represents an early phase of invasive germ cell neoplasia.
一名自出生起就患有双侧隐睾的13岁男性，在被诊断为恶性生殖细胞肿瘤后接受了睾丸活检及随后的左侧睾丸切除术。尽管在生精小管和间质中可见恶性细胞，但未发现肿瘤肿块。回顾了5例已记录的睾丸原位或早期生殖细胞肿瘤病例；其中3例不育，另一例有隐睾，第5例既不育又有隐睾。这些患者中有2例已发展为明显的癌，这表明该过程代表了侵袭性生殖细胞瘤的早期阶段。
