Florey C D, Taylor D J
Department of Epidemiology and Public Health University of Dundee, Ninewells Hospital and Medical School, UK.
Rev Epidemiol Sante Publique. 1994;42(3):191-7.
The relation between gestational age at first antenatal visit and infant's birth weight was investigated in a cohort study of 846 primiparas living in the City of Dundee, Scotland, whose first antenatal visit was between 1 May 1985 and 30 April 1986. The earlier in pregnancy the first antenatal visit the greater the infants' birth weights tended to be (p < 0.01). The relation was independent of gestational age at birth, mother's age and height, social class, tobacco and alcohol consumption and the child's sex. The result supports similar findings elsewhere, but is more robust in that, in contrast to other studies, all birth weights were measured on a single electronic scale and the effects of maternal tobacco and alcohol consumption on birth weight were taken into account in the analysis. The mechanism of the effect remains to be determined but needs to be identified as it may indicate possible preventive measures for the benefit of future children.
在一项队列研究中，对居住在苏格兰邓迪市的846名初产妇进行了调查，这些产妇的首次产前检查时间在1985年5月1日至1986年4月30日之间，研究了首次产前检查时的孕周与婴儿出生体重之间的关系。首次产前检查的时间越早，婴儿的出生体重往往越大（p<0.01）。这种关系独立于出生时的孕周、母亲的年龄和身高、社会阶层、烟草和酒精消费以及孩子的性别。该结果支持了其他地方的类似发现，但更为可靠，因为与其他研究不同的是，所有出生体重均使用单一电子秤测量，并且在分析中考虑了母亲烟草和酒精消费对出生体重的影响。这种影响的机制仍有待确定，但需要加以识别，因为它可能表明有利于未来儿童的可能预防措施。
