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[Levamisole in children with frequently recurring idiopathic nephrotic syndrome].

作者信息

Meregalli P, Bianchetti M G, Imoberdorf G, Lütschg J, Reymond D, Oetliker O H

机构信息

Abteilung für Nephrologie, Medizinischen Universitäts-Kinderklinik Bern.

出版信息

Schweiz Med Wochenschr. 1994 May 14;124(19):801-5.

PMID:8209202
Abstract

10 children (8 boys and 2 girls) with frequently relapsing idiopathic nephrotic syndrome were treated with levamisole (5 mg/kg weekly). In 6 children with steroid dependent nephrotic syndrome a marked reduction in steroids by 62% to 75% was possible. Severe, transient neutropenia was observed in one patient. Levamisole failed to influence the disease course positively in 3 patients with relapses associated with intercurrent illness. It is concluded that levamisole may favourably influence steroid dependence in children with frequently relapsing idiopathic nephrotic syndrome.

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