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十二指肠消化性溃疡和胃十二指肠炎症与慢性葡萄球菌感染的关系

[The relationship of duodenal peptic ulcer and gastroduodenitis to a chronic staphylococcal infection].

作者信息

Zavadiak M I

出版信息

Lik Sprava. 1993 May-Jun(5-6):65-9.

PMID:8209503
Abstract

Tonsillar and pharyngeal smears revealed growth of pathogenic microorganisms, mainly of Staphylococcus aureus, in 58.0 +/- 3.7% of 174 patients with duodenal ulcer and gastroduodenitis during remission or unstable remission, in 40.0 +/- 5.3% of 85 patients with other gastroenterological diseases and in 17.5 +/- 6.0% of 40 subjects constituting control group. Urease activity ratio (biological marker of Helicobacter pylori) was found to be approximately the same in every group of patients vs 11.1 +/- 6.2% of 27 healthy persons. Pathogenetic mechanisms of relation between duodenal ulcer, chronic gastroduodenitis and chronic focuses of infection are discussed. Lymphatic pharyngeal ring is supposed to be biotopical for Helicobacter pylori.

摘要

对174例处于缓解期或缓解不稳定期的十二指肠溃疡和胃十二指肠炎症患者进行扁桃体和咽部涂片检查,结果显示58.0±3.7%的患者有致病微生物生长,主要是金黄色葡萄球菌;85例患有其他胃肠疾病的患者中,这一比例为40.0±5.3%;而在由40名受试者组成的对照组中,这一比例为17.5±6.0%。与27名健康人(11.1±6.2%)相比,每组患者的尿素酶活性比率(幽门螺杆菌的生物学标志物)大致相同。文中讨论了十二指肠溃疡、慢性胃十二指肠炎症与慢性感染病灶之间关系的发病机制。淋巴咽环被认为是幽门螺杆菌的生物栖息地。

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