Garnett G P, Anderson R M
Parasite Epidemiology Research Group, Imperial College, London, England.
Sex Transm Dis. 1993 Jul-Aug;20(4):181-91. doi: 10.1097/00007435-199307000-00001.
The concept of a core group of individuals who change sexual partners frequently has played an important role in the study of the epidemiology of sexually transmitted diseases (STDs). It is widely believed that the core group is important in the persistence of infection and that it provides a sensible target for control interventions. GOAL OF THIS STUDY AND STUDY DESIGN: Simple mathematical models are used to assess the significance of sexual mixing between core and noncore groups. Published data from contact tracing studies, which base the definition of the core group on gonorrhea incidence by area of residence, are used to derive estimates of the degree of mixing within and between groups.
Analyses reveal patterns of high mixing within core groups in the urban study sites, which suggests that within-group transmission ensures the persistence of gonococcal infection in the community as a whole.
An extension of the analysis of contact tracing data to facilitate the development of mathematical models of STD transmission is detailed.
性伴侣更换频繁的核心人群概念在性传播疾病（STD）流行病学研究中发挥了重要作用。人们普遍认为，核心人群对于感染的持续存在至关重要，并且它为控制干预措施提供了一个合理的目标。本研究的目的及研究设计：使用简单的数学模型来评估核心人群与非核心人群之间性接触的重要性。利用接触者追踪研究的已发表数据（这些研究根据居住区域的淋病发病率来定义核心人群）来推导组内和组间接触程度的估计值。
分析揭示了城市研究地点核心人群内部高度接触的模式，这表明组内传播确保了淋病感染在整个社区中的持续存在。
详细阐述了对接触者追踪数据进行扩展分析以促进性传播疾病传播数学模型的开发。
