Aleshin I A, Kots Ia I, Tverdokhlib V P, Galiautdinov G S, Vdovenko L G, Zabirov M R, Meerson F Z
Ter Arkh. 1993;65(8):23-9.
Patients with essential hypertension were exposed to periodic hypoxia in a pressure chamber. It is shown that adaptation to periodic hypoxia results in improvement of general condition of patients who exhibited a decline in blood pressure, minute blood volume, serum sodium concentrations as well as better microcirculation and tissue oxygen tension. Reduced concentrations of total serum cholesterol and atherogenic index were achieved in hypercholesterolemia patients. The changes obtained permitted reduction of hypotensive maintenance treatment. In view of positive results in hypertensive subjects, adaptation to periodic hypoxia in a pressure chamber is recommended for inclusion into combined regimens of hypertension therapy.
原发性高血压患者在压力舱中接受周期性低氧暴露。结果显示，适应周期性低氧可改善患者的总体状况，患者的血压、每分钟血容量、血清钠浓度均有所下降，微循环和组织氧张力也得到改善。高胆固醇血症患者的血清总胆固醇浓度和致动脉粥样硬化指数降低。这些变化使得降压维持治疗得以减少。鉴于高血压患者取得的积极结果，建议将在压力舱中适应周期性低氧纳入高血压治疗的联合方案。
