Button L N, Jacobson M S, Kevy S V
Transfusion. 1976 Jul-Aug;16(4):307-11. doi: 10.1046/j.1537-2995.1976.16476247050.x.
Rhesus monkey platelets that are separated, 51Cr labeled, and transfused provide yields, 1/2 time and survivals similar to those obtained in man. Rhesus platelets prepared and stored at room temperature for three days have 93 per cent of the yield of fresh platelets. When prepared and stored at 4C, the yield is only 54 per cent of fresh platelets. Rhesus repeatedly transfused with platelets from random unmatched donors always have a significant decrease in the platelet 1/2 time and survival. This was observed after the second homologous transfusion in one and after the third in others. The rhesus provides an excellent platelet model with thrombocyte responses mimicking those of man.
分离、用51Cr标记并输注的恒河猴血小板所产生的产量、半衰期和存活率与人的情况相似。在室温下制备并储存三天的恒河猴血小板产量为新鲜血小板的93%。当在4℃下制备并储存时，产量仅为新鲜血小板的54%。恒河猴反复输注来自随机不匹配供体的血小板后，血小板半衰期和存活率总是显著降低。在一只恒河猴第二次同种异体输血后以及其他恒河猴第三次输血后观察到这种情况。恒河猴提供了一个极好的血小板模型，其血小板反应与人的相似。
