Rosenthal M, Cramer D, Bain S H, Denison D, Bush A, Warner J O
Department of Paediatric Respiratory Medicine, Royal Brompton National Heart and Lung Hospital, London.
Thorax. 1993 Aug;48(8):803-8. doi: 10.1136/thx.48.8.803.
A study was performed to determine reference ranges for whole body plethysmographic gas volumes and single breath gas transfer in healthy prepubertal and pubertal schoolchildren.
The study was performed in 772 white London schoolchildren (455 male) who were clinically examined, assessed auxologically and, in 63% of cases, pubertally staged. Regression equations for the calculation of standard deviation scores were derived.
Male lung function variables showed a discontinuous pattern of increase with standing height. Linear increases until puberty were followed by a sudden pubertal rise and a further increase with height which was more marked than before puberty. Correction for varying thoracic dimensions eliminated these changes. In females a smoother curvilinear relationship was observed with no correction possible for thoracic size.
Male puberty leads to profound changes in pulmonary function mostly related to thoracic size, an effect not observed in females.
开展一项研究以确定健康的青春期前和青春期学童全身体积描记法气体容积和单次呼吸气体交换的参考范围。
该研究纳入了772名伦敦白人学童（455名男性），对他们进行了临床检查、体格评估，63%的病例进行了青春期分期。得出了用于计算标准差分数的回归方程。
男性肺功能变量随身高呈不连续增加模式。青春期前呈线性增加，随后青春期突然上升，且随身高进一步增加，这比青春期前更为明显。对不同胸廓尺寸进行校正消除了这些变化。在女性中观察到更平滑的曲线关系，胸廓尺寸无法校正。
男性青春期导致肺功能发生深刻变化，主要与胸廓尺寸有关，女性未观察到这种影响。
