Nielsen J D, Pedersen N F, Olesgaard P
Ugeskr Laeger. 1993 Aug 30;155(35):2703-5.
This paper presents a retrospective study of asymptomatic bacteriuria from general practice. The general practitioner had screened children's urine specimens for asymptomatic bacteriuria at the eight regular health examinations during preschool age. The urine was collected in special adhesive bags or as a midstream clean catch and investigated by stix and culture at the practitioner's. When significant bacteriuria was noted, a new urine sample was collected for analysis. If asymptomatic bacteriuria was again noted, the culture plates were sent to a microbiological hospital department for determination of bacterial type and antibiotic resistance. The children were subsequently treated with a relevant antibiotic. The material collected during 12 years consisted of 658 urine samples obtained from 1295 examinations of 208 children. Thirty-five samples (5.3%) were positive, and 30 of the children presented at least one positive sample (14.2%). Most of the positive samples were obtained during the first two years. However, the material is too small to obtain statistically positive results and must due to its retrospective nature be interpreted with care. Nevertheless, the high rate of infection in our study motivates the initiation of a regular prospective study.
本文呈现了一项针对全科医疗中无症状菌尿症的回顾性研究。全科医生在学龄前儿童的八次定期健康检查中对其尿液标本进行无症状菌尿症筛查。尿液通过特殊粘贴袋收集或采用中段清洁尿样采集,由医生使用试纸条和培养法进行检测。当发现显著菌尿时,会采集新的尿样进行分析。若再次发现无症状菌尿,培养平板会被送往医院微生物科以确定细菌类型和抗生素耐药性。随后这些儿童接受相关抗生素治疗。12年间收集的资料包括从208名儿童的1295次检查中获取的658份尿样。35份样本(5.3%)呈阳性,其中30名儿童至少有一份阳性样本(14.2%)。大多数阳性样本是在前两年获得的。然而,该资料规模过小,无法得出具有统计学意义的阳性结果,且由于其回顾性特点,在解读时必须谨慎。尽管如此,我们研究中较高的感染率促使开展一项定期前瞻性研究。