Dangas N, Parashou E, Lymberi M, Kehayas P
Department of Urology, Hippokration General Hospital, Athens, Greece.
Urol Res. 1993;21(4):257-60. doi: 10.1007/BF00307706.
This experimental study was designed to investigate the possibility of an interaction between elevated intravesical pressure and urinary sodium excretion. Fourteen male New Zealand rabbits were used. After performing a ureterocutaneous diversion, urinary sodium excretion was measured in two situations: with the bladder empty and with the bladder overdistended and an intravesical pressure of 60 cm H2O. There was a significant decrease in urinary sodium excretion at an elevated intravesical pressure. The urinary sodium excretion returned to normal after relief of the pressure. The results suggest the existence of a neurogenic pathway activated by the elevated intravesical pressure.
本实验研究旨在探讨膀胱内压升高与尿钠排泄之间相互作用的可能性。使用了14只雄性新西兰兔。在进行输尿管皮肤造口术后，在两种情况下测量尿钠排泄：膀胱空虚时以及膀胱过度扩张且膀胱内压为60 cm H2O时。膀胱内压升高时尿钠排泄显著减少。压力解除后尿钠排泄恢复正常。结果提示存在一条由膀胱内压升高激活的神经源性途径。
