对红细胞上可用G（重组人促红细胞生成素，Rh12）抗原位点数量的观察。

Observations of the number of available G (rhG, Rh12) antigen sites on red cells.

作者信息

Skov F

出版信息

Vox Sang. 1976;31(2):124-30. doi: 10.1111/j.1423-0410.1976.tb02198.x.

DOI:10.1111/j.1423-0410.1976.tb02198.x

Abstract

The number of available G antigen sites within the rhesus system were estimated using trace-labelled antibody. The results given as available antigen sites per cell were as follows: R1R1: 9,900-12,200; r'r': 8,200-9,700; ryr: 8,600; RNRN: 6,600; r'xr: 6,200; RB1r: 6,200; RZRZ: 5,400; Cdes: 4,800-5,100; R2R2: 3,600-5,800; RORO: 4,500-5,300; R2r 4,200; r''Gr: 1,700-3,600; RB2r: 1,400-1,900. The G antigen is detected in optimal amount on C-positive samples. When D is present without C,the number of G sites is apparently dependent on the expression of all the D antigens within the recognized six categories of D antigens.

摘要

使用微量标记抗体估计恒河猴系统中可用G抗原位点的数量。以每个细胞的可用抗原位点给出的结果如下：R1R1：9900 - 12200；r'r'：8200 - 9700；ryr：8600；RNRN：6600；r'xr：6200；RB1r：6200；RZRZ：5400；Cdes：4800 - 5100；R2R2：3600 - 5800；RORO：4500 - 5300；R2r 4200；r''Gr：1700 - 3600；RB2r：1400 - 1900。在C阳性样本上能检测到最佳量的G抗原。当存在D而无C时，G位点的数量显然取决于已识别的六类D抗原中所有D抗原的表达。