Carstensen F, Wurbs D
3. Medizinische Abteilung und Gastroenterologie des Allgemeinen Krankenhauses Barmbek, Hamburg.
Z Gastroenterol. 1993 Jun;31(6):369-75.
During this study the absorption rates of two contrast media were measured in double-blind design. 33 patients received lopamidol (Solutrast 300), and 30 patients Meglumine iothalamate (Conray 60). A regular absorption of the contrast media during ERC, ERP and ERCP could be stated. With reference to the absorption rates a slight, but for statistically not significant advantage for the contrast medium lopamidol could be ascertained. During ERC the absorption rates ranged from 0.4 to 30%, during ERP from 2.2 to 18.8% and during ERCP from 1.0 and 30.0%. Consequently the endoscopist always has to take into account an anaphylactoid reaction due to the systemic absorption of contrast media which, compared to other examinations with contrast media, happens relatively seldom.
在本研究中,采用双盲设计测量了两种造影剂的吸收率。33例患者接受了碘帕醇(Solutrast 300),30例患者接受了碘他拉葡胺(Conray 60)。可以确定在逆行胰胆管造影(ERC)、内镜逆行胰管造影(ERP)和内镜逆行胰胆管造影(ERCP)期间造影剂有规律的吸收。关于吸收率,可确定造影剂碘帕醇有轻微优势,但在统计学上不显著。在ERC期间,吸收率范围为0.4%至30%,在ERP期间为2.2%至18.8%,在ERCP期间为1.0%至30.0%。因此,内镜医师必须始终考虑到由于造影剂的全身吸收而引起的类过敏反应,与其他使用造影剂的检查相比,这种情况相对较少发生。