Gordon P C, Kugelmass A D, Cohen D J, Breall J A, Friedrich S P, Carrozza J P, Diver D J, Kuntz R E, Baim D S
Charles A. Dana Research Institute, Beth Israel Hospital, Boston, Massachusetts.
Am J Cardiol. 1993 Oct 18;72(13):71E-79E. doi: 10.1016/0002-9149(93)91041-f.
This study investigates whether adjunctive balloon angioplasty can be safely used to improve acute results in cases where directional coronary atherectomy alone has provided a successful (but suboptimal) outcome. Between October 1, 1990, and October 1, 1992, directional coronary atherectomy was performed successfully in 198 of 228 lesions. Individual operators believed that most acute results were satisfactory after atherectomy alone (group I, n = 115) with a minimal lumen diameter that increased from 0.82 +/- 0.45 to 3.21 +/- 0.65 mm after atherectomy, for an acute gain in lumen diameter of 2.39 +/- 0.73 mm and a residual stenosis of 6 +/- 13%. In 42% of lesions (group II, n = 83), however, results were considered suboptimal after atherectomy alone, with a minimal lumen diameter that increased from 0.85 +/- 0.45 to 2.83 +/- 0.64 mm, a smaller acute gain of 1.96 +/- 0.72 mm, and a mean residual stenosis of 17 +/- 14% (although all residual stenoses were < 50%, 19% had a residual stenosis > 30%). Adjunctive balloon angioplasty in these group II lesions provided an additional gain of 0.34 +/- 0.38 mm, bringing the total acute gain for group II lesions to 2.32 +/- 0.78 mm and the residual stenosis to 9 +/- 13%, similar to that of group I patients who underwent atherectomy alone. This strategy resulted in a 7 +/- 13% overall residual stenosis for the study population, with no higher incidence of periprocedural complications or adverse late clinical outcomes in group II patients.(ABSTRACT TRUNCATED AT 250 WORDS)
本研究旨在调查在仅采用定向冠状动脉斑块旋切术已取得成功(但未达最佳效果)的病例中,辅助性球囊血管成形术能否安全用于改善急性治疗效果。在1990年10月1日至1992年10月1日期间,228处病变中有198处成功实施了定向冠状动脉斑块旋切术。个别术者认为,仅行斑块旋切术后多数急性治疗效果令人满意(I组,n = 115),最小管腔直径从旋切术前的0.82±0.45 mm增加至旋切术后的3.21±0.65 mm,管腔直径急性增加2.39±0.73 mm,残余狭窄为6±13%。然而,在42%的病变(II组,n = 83)中,仅行斑块旋切术后效果被认为未达最佳,最小管腔直径从0.85±0.45 mm增加至2.83±0.64 mm,急性增加较小,为1.96±0.72 mm,平均残余狭窄为17±14%(尽管所有残余狭窄均<50%,但19%的残余狭窄>30%)。对这些II组病变行辅助性球囊血管成形术可使管腔直径额外增加0.34±0.38 mm,使II组病变的总急性增加量达2.32±0.78 mm,残余狭窄达9±13%,与仅行斑块旋切术的I组患者相似。该策略使研究人群的总体残余狭窄为7±13%,II组患者围手术期并发症或不良晚期临床结局的发生率未升高。(摘要截选至250词)