Mascia A V, Friedman E A, Kornfield M A
Ann Allergy. 1976 Jul;37(1):1-7.
Cromolyn sodium was administered by inhalation four times a day to 53 severely asthmatic children for periods ranging from 10 to 43 months. The patients were seen at follow-up vists at least once a month through the entire study period. At the cut-off point of the study cromolyn sodium had been effective in controlling asthma by reducing the level of asthma symptoms, such as coughing, wheezing, sleep disturbance and sputum output. In addition there was a reduction in the patients' requirements for concomitant anti-asthma medications (including corticosteroids) and the number of hospitalizations and school absences.
对53名重度哮喘儿童每天进行4次吸入色甘酸钠治疗，疗程为10至43个月。在整个研究期间，患者至少每月接受一次随访。在研究截止时，色甘酸钠通过降低哮喘症状水平（如咳嗽、喘息、睡眠障碍和痰液排出量）有效控制了哮喘。此外，患者对联合使用的抗哮喘药物（包括皮质类固醇）的需求、住院次数和缺课天数均有所减少。
