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艾滋病毒感染与静脉注射吸毒:新泽西州埃塞克斯县和哈德逊县法医案例

HIV infection and i.v. drug use: medical examiner cases in Essex and Hudson Counties, New Jersey.

作者信息

Haberman P W, French J F, Chin J

机构信息

New Jersey Department of Health, Division of Alcoholism, Trenton 08625-0362.

出版信息

Am J Drug Alcohol Abuse. 1993;19(3):299-307. doi: 10.3109/00952999309001620.

DOI:10.3109/00952999309001620
PMID:8213694
Abstract

Patterns of HIV infection and IV drug use in 697 Essex and Hudson Counties, New Jersey, 1986-1987 Medical Examiner (ME) cases, aged 15-59 years, were examined. All cases had toxicology tests for drugs and had been autopsied. Postmortem stored sera were blind-tested and confirmed for the presence of HIV-1-antibody by the New Jersey Department of Health. All cases and IV drug users were dichotomized according to the presence/absence of HIV-1-antibody and were then analyzed for differences in demographic and postmortem characteristics. Subjects were predominantly Black men aged 30-44 years; the 119 HIV(+) cases were even more likely to be Black or Hispanic and in the 30-44 age group. Evidence of IV drug use and HIV(+) status were very highly correlated; 86 of 181 IV drug users were HIV(+). There was a low rate of suicide among HIV(+) cases and IV drug users. Only 3 of 63 suicide victims were HIV(+), and they were the only IV drug users whose manner of death was certified as suicide. Cases with toxicology findings of both heroin and cocaine were most likely to be HIV(+), followed in order by those with heroin or cocaine alone present. Cocaine alone was the illicit drug most often present in toxicology tests on all cases. Among IV drug users, heroin with cocaine was most often present.

摘要

对1986 - 1987年新泽西州埃塞克斯县和哈德逊县697例年龄在15至59岁之间的法医(ME)病例的艾滋病毒感染模式和静脉吸毒情况进行了检查。所有病例都进行了毒品毒理学检测并已进行尸检。对死后储存的血清进行了盲法检测,并由新泽西州卫生部确认是否存在HIV - 1抗体。所有病例和静脉吸毒者根据是否存在HIV - 1抗体进行二分法分类,然后分析其人口统计学和死后特征的差异。研究对象主要是30至44岁的黑人男性;119例HIV(+)病例更有可能是黑人或西班牙裔,且在30至44岁年龄组。静脉吸毒证据与HIV(+)状态高度相关;181名静脉吸毒者中有86人HIV(+)。HIV(+)病例和静脉吸毒者中的自杀率较低。63名自杀受害者中只有3人HIV(+),他们是仅有的死亡方式被认定为自杀的静脉吸毒者。毒理学检测结果同时发现海洛因和可卡因的病例最有可能HIV(+),其次依次是仅发现海洛因或可卡因的病例。在所有病例的毒理学检测中,单独出现的可卡因是最常出现的非法药物。在静脉吸毒者中,最常出现的是海洛因和可卡因同时存在。

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