Stetson D S, Silverstein B A, Keyserling W M, Wolfe R A, Albers J W
School of Public Health, University of Michigan, Ann Arbor.
Am J Ind Med. 1993 Aug;24(2):175-89. doi: 10.1002/ajim.4700240205.
To test for associations between occupation and median nerve dysfunction, measures of median motor and median and ulnar sensory amplitude and distal latency were compared among three populations: control subjects without occupational exposure to highly forceful or repetitive hand exertions (N = 105), industrial workers with hand/wrist symptoms (N = 103), and asymptomatic industrial workers (N = 137). Mean sensory amplitudes were significantly smaller (p < 0.05) and motor and sensory distal latencies were significantly longer (p < 0.001) in the industrial "asymptomatic hand" population compared to the control population. Prolongation of median relative to ulnar latency was significantly longer in the asymptomatic industrial population (p < 0.05). Results were most plausibly explained by differences in checklist identified ergonomic stressors. Median sensory amplitudes were significantly smaller (p < 0.01) and latencies longer (p < 0.05) for industrial workers with exposure to high grip forces compared to those without. Exposure misclassification may have reduced power to detect statistically significant differences between exposed and nonexposed population groups.
为了测试职业与正中神经功能障碍之间的关联,比较了三组人群的正中运动、正中及尺侧感觉振幅和远端潜伏期测量值:无职业性强力或重复性手部用力暴露的对照受试者(N = 105)、有手/腕部症状的产业工人(N = 103)和无症状产业工人(N = 137)。与对照人群相比,产业“无症状手部”人群的平均感觉振幅显著更小(p < 0.05),运动和感觉远端潜伏期显著更长(p < 0.001)。无症状产业人群中正中相对于尺侧潜伏期的延长显著更长(p < 0.05)。结果最合理的解释是检查表确定的人体工程学应激源的差异。与未暴露于高握力的产业工人相比,暴露于高握力的产业工人的正中感觉振幅显著更小(p < 0.01),潜伏期更长(p < 0.05)。暴露错误分类可能降低了检测暴露人群和未暴露人群组之间统计学显著差异的能力。