Emeriau J P, Le Menn R, Besse P, Bricaud H
Arch Mal Coeur Vaiss. 1976 May;69(5):475-83.
A fragment of septum was removed for biopsy in 11 patients with obstructive cardiomyopathy who were undergoing surgery. Electron microscopi revealed an increase in the numbers of mitochondria, deposits of glycogen, and deforming fibrosis. As far as the components of muscle fibres are concerned, both lysis and synthesis of neosarcomeres are to be found, together with abnormalities of the Z band and disorientation of the myofibrils. The number and severity of these abnormalities were found to vary from patient to patient and also in different sections. Although these features are virtually constant in cases of obstructive cardiomyopathy, they are not specific for this condition; they are also found in cases of non-obstructive hypertrophic cardiomyopathy.
对11例接受手术的梗阻性心肌病患者切除部分间隔进行活检。电子显微镜检查显示线粒体数量增加、糖原沉积以及变形性纤维化。就肌纤维成分而言，可见新肌节的溶解和合成，同时伴有Z带异常和肌原纤维排列紊乱。发现这些异常的数量和严重程度因患者而异，在不同切片中也有所不同。虽然这些特征在梗阻性心肌病病例中几乎是恒定的，但并非该疾病所特有；在非梗阻性肥厚型心肌病病例中也可发现。
