Bouhour J B, Petitier H, De Lajartre A Y, Almazor M, Nicolas G, Horeau J
Arch Mal Coeur Vaiss. 1976 May;69(5):485-94.
38 patients with congestive cardiomyopathy of apparantly primary origin had a myocardial biopsy. The histology of the fragment of myocardium was studied both by light microscopy and electron microscopy. The results were compared with those from 3 "control" cases and with 16 cases of congestive asystole secondary to a known cause. The non-specific patternss which were observed were of 3 types: patterns of degeneration, pattern of hypertrophy, and interstitial fibrosis. Chronic alcholism had no modifying effect on the ultrastructure. Finally, the group in which the morphology was altered had a higher mortality, but the prognostic significance of the degree of severity of the morphological change must be treated with caution in each individual case.
38例明显原发性充血性心肌病患者接受了心肌活检。通过光学显微镜和电子显微镜对心肌片段的组织学进行了研究。将结果与3例“对照”病例以及16例继发于已知病因的充血性心搏停止病例的结果进行了比较。观察到的非特异性模式有3种:变性模式、肥大模式和间质纤维化模式。慢性酒精中毒对超微结构无修饰作用。最后,形态发生改变的组死亡率较高,但在每个个体病例中,形态学改变严重程度的预后意义必须谨慎对待。