Takatani S, Shiono M, Sasaki T, Orime Y, Sakuma I, Noon G, Nosé Y, DeBakey M
Department of Surgery, Baylor College of Medicine, Houston, Texas 77030.
Artif Organs. 1993 Mar;17(3):176-84. doi: 10.1111/j.1525-1594.1993.tb00427.x.
Left master alternate (LMA) ejection control based on the left pump fill method was implemented for a one-piece electromechanical total artificial heart (TAH). The TAH consists of left and right pusher-plate-type blood pumps sandwiching a compact electromechanical actuator comprising a direct current (DC) brushless motor and a planetary roller screw. The motor rotation is controlled on the basis of the roller-screw position as detected by a Hall effect sensor and a commutation pulse counting method. Since the pusher-plate shaft and roller screw are decoupled during filling, both pumps fill passively with the right and left atrial pressure. To obtain response to the right atrial pressure change in the LMA mode, the left fill trigger level as detected by a Hall effect position sensor is adjusted to operate the pump at a higher rate and to drive the right pump at 85-90% of the full stroke level. The in vitro evaluation demonstrated that this method can respond to right atrial pressure changes provided that the right pump is operated at less than the full stroke level. When the preload is high and the right pump goes into full stroke operation, the left eject level can be decreased to run the pump at a higher rate and to transfer more blood from the right to the left. In the in vivo evaluation, which lasted 1 week in a 95 kg calf, the left and right atrial pressures were kept within physiological ranges.(ABSTRACT TRUNCATED AT 250 WORDS)
基于左泵充盈方法的左主交替(LMA)射血控制应用于一体式机电全人工心脏(TAH)。该TAH由左右推板式血泵组成,中间夹着一个紧凑的机电致动器,该致动器包括直流(DC)无刷电机和行星滚柱丝杠。电机旋转根据霍尔效应传感器检测到的滚柱丝杠位置和换向脉冲计数方法进行控制。由于在充盈过程中推板轴和滚柱丝杠解耦,两个泵均被动地随左右心房压力充盈。为了在LMA模式下获得对右心房压力变化的响应,由霍尔效应位置传感器检测到的左充盈触发水平被调整,以使泵以更高的速率运行,并驱动右泵至全行程水平的85 - 90%。体外评估表明,只要右泵以低于全行程水平运行,该方法就能响应右心房压力变化。当预负荷较高且右泵进入全行程运行时,左射血水平可以降低,以使泵以更高的速率运行,并将更多血液从右向左输送。在对一头95千克小牛进行的为期1周的体内评估中,左右心房压力保持在生理范围内。(摘要截断于250字)