1,2,3-Triazole[4,5-d]pyridazines--I. Analogues of prostaglandin synthesis inhibitors.
作者信息
Biagi G, Ferretti M, Giorgi I, Livi O, Scartoni V, Lucacchini A
机构信息
Istituto di Chimica Farmaceutica e Tossicologica, Facoltà di Farmacia, Pisa.
出版信息
Farmaco. 1993 Aug;48(8):1159-65.
PMID:8216677
Abstract
This paper reports the preparation of new triazolepyridazine derivatives bearing in the 1 position an acidic substituent, on the basis of a working hypothesis relating these compounds to 1,2,3-triazole derivatives, effective in vitro inhibitors of the prostaglandin synthesis. The tested compounds were lacking of biological activity.
摘要
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