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1,2,3-Triazole[4,5-d]pyridazines--I. Analogues of prostaglandin synthesis inhibitors.

作者信息

Biagi G, Ferretti M, Giorgi I, Livi O, Scartoni V, Lucacchini A

机构信息

Istituto di Chimica Farmaceutica e Tossicologica, Facoltà di Farmacia, Pisa.

出版信息

Farmaco. 1993 Aug;48(8):1159-65.

PMID:8216677
Abstract

This paper reports the preparation of new triazolepyridazine derivatives bearing in the 1 position an acidic substituent, on the basis of a working hypothesis relating these compounds to 1,2,3-triazole derivatives, effective in vitro inhibitors of the prostaglandin synthesis. The tested compounds were lacking of biological activity.

摘要

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