[抗IgE诱导变应性鼻炎嗜碱性粒细胞释放能力的研究]
[Study on basophil releasability induced by anti-IgE in allergic rhinitis].
作者信息
Gu M L
机构信息
Central Hospital, Shengli Petroleum Administration, Dongying, Shandong.
出版信息
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1993;28(2):77-8, 123-4.
We have investigated the basophil releasability induced by anti-IgE in allergic rhinitis patients and normal subjects by reverse human basophil degranulation tests. The results showed that anti-IgE-mediated basophil releasability and total serum IgE were significantly higher in allergic rhinitis patients than that in normal subjects. However, anti-IgE-mediated basophil releasability, total serum IgE and blood eosinophil count were not closely correlated with each other.
我们通过反向人嗜碱性粒细胞脱颗粒试验，研究了抗IgE在过敏性鼻炎患者和正常受试者中诱导的嗜碱性粒细胞释放能力。结果显示，过敏性鼻炎患者中抗IgE介导的嗜碱性粒细胞释放能力和血清总IgE显著高于正常受试者。然而，抗IgE介导的嗜碱性粒细胞释放能力、血清总IgE和血液嗜酸性粒细胞计数之间并无密切相关性。
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