Shen J X
Union Hospital, Tongji Medical University, Wuhan.
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1993;28(2):74-6, 123.
Observing the basophil releasability of 17 patients with allergic rhinitis and 14 nonatopic subjects stimulated with house dust mite and concanavalin A (ConA), we found that the histamine release was much higher in patients with allergic rhinitis than in normal controls and that no positive correlation was found between the histamine release rate and the serum total IgE. This result suggests that the enhanced basophil releasability might be an important factor in allergic disorders, and might contribute to a means for the differentiation between allergic and non-allergic disorders.
观察17例变应性鼻炎患者和14名非特应性受试者在屋尘螨和伴刀豆球蛋白A（ConA）刺激下的嗜碱性粒细胞释放能力，我们发现变应性鼻炎患者的组胺释放比正常对照高得多，且组胺释放率与血清总IgE之间未发现正相关。该结果提示，增强的嗜碱性粒细胞释放能力可能是变应性疾病中的一个重要因素，且可能有助于区分变应性和非变应性疾病。
