Alanen K A, Joensuu H
Department of Pathology, University of Turku, Finland.
Br J Cancer. 1993 Nov;68(5):1004-5. doi: 10.1038/bjc.1993.469.
Prognosis of adenocarcinoma of the pancreas has remained poor, but a few patients are reported to live 5 years or longer after the diagnosis. Using the data of the Finnish Cancer Registry, we could identify only 78 patients (1.3%) who had survived for longer than 5 years after the diagnosis of pancreatic cancer among 5,837 patients diagnosed in Finland in 1975-1984. However, in 33 of the 78 cases a histological diagnosis of pancreatic cancer had never been made, and the majority of the remaining 45 patients turned out not to have pancreatic adenocarcinoma after a review. The results suggest that the majority of patients with long-term survival following the diagnosis of pancreatic cancer have never had pancreatic adenocarcinoma. Taking a biopsy from a suspected pancreatic neoplasm and careful histological evaluation may prohibit misdiagnosis of this highly lethal disease.
胰腺癌的预后一直很差，但据报道，少数患者在确诊后能存活5年或更长时间。利用芬兰癌症登记处的数据，在1975年至1984年芬兰确诊的5837例胰腺癌患者中，我们仅能识别出78例（1.3%）在确诊后存活超过5年的患者。然而，在这78例病例中，有33例从未进行过胰腺癌的组织学诊断，在复查后，其余45例患者中的大多数最终被证实并非胰腺腺癌。结果表明，大多数胰腺癌确诊后长期存活的患者从未患过胰腺腺癌。对疑似胰腺肿瘤进行活检并进行仔细的组织学评估，可能会避免对这种高致死性疾病的误诊。
