癌症研究中的病理学综述。
Pathology review in cancer research.
作者信息
Freedman L S, Machin D
出版信息
Br J Cancer. 1993 Nov;68(5):827-30. doi: 10.1038/bjc.1993.440.
Abstract
Pathology observer agreement studies are clearly important in the development of new pathology assessments and in the quality control of those assessments in common use. Setting up such studies, and reporting and interpreting their results requires careful thought and statistical expertise. Investigators are advised to seek collaboration with a statistician before embarking on these studies. Pathology reference panel reviews in multicentre studies are useful for checking eligibility when there is a high level of disagreement on the eligibility criterion between local pathologists and the reference panel members, but good agreement between members of the panel. However, such situations are uncommon.
摘要
病理学观察者一致性研究对于新病理学评估方法的开发以及常用评估方法的质量控制显然至关重要。开展此类研究、报告并解读其结果需要仔细思考和统计学专业知识。建议研究人员在着手进行这些研究之前寻求与统计学家的合作。在多中心研究中进行病理学参考小组审查，当本地病理学家与参考小组成员在资格标准上存在高度分歧，但小组成员之间一致性良好时，有助于检查资格。然而，这种情况并不常见。
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