舒洛地尔的抗血小板和抗血栓形成作用。
Antiplatelet and antithrombogenic effects of suloctidil.
作者信息
Roba J, Claeys M, Lambelin G
出版信息
Eur J Pharmacol. 1976 Jun;37(2):265-74. doi: 10.1016/0014-2999(76)90034-0.
PMID:821760
Abstract
Platelet aggregation induced in mice or rats by i.v. ADP can be antagonized by oral administration of suloctidil. This effect on platelet behaviour appears to be sufficient to reduce the rate of thrombotic occlusion of the femoral artery in the dog and to protect the rat against occurrence of thrombophlebitis.
摘要
静脉注射ADP诱导的小鼠或大鼠血小板聚集可通过口服舒洛地尔予以拮抗。这种对血小板行为的作用似乎足以降低犬股动脉血栓闭塞的发生率，并保护大鼠预防血栓性静脉炎的发生。
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