Souchier C, Manel A M, Ffrench M, Treilleritouet D, Bryon P A
Cytologie Analytique, Lyon, France.
In Vivo. 1993 Jul-Aug;7(4):339-42.
Description of morphological and textural changes during cell cycle were studied in 31 diploid Acute Lymphoid Leukemia ALL cases. Feulgen stained nuclei were measured by image analysis. Cells with 2C, 3C and 4C content of DNA were considered as being in G1, S and G2 phase of cell cycle respectively. The main observed transformations associated with cell cycle were continuous increases in nuclear size and in quantities of black/white chromatin clumps and points. An overall correct classification of 92.5% was achieved by multivariate data analysis. However, significant differences between A L L cases were noticed.
在31例二倍体急性淋巴细胞白血病（ALL）病例中研究了细胞周期中形态和纹理变化的描述。通过图像分析对福尔根染色的细胞核进行测量。DNA含量为2C、3C和4C的细胞分别被认为处于细胞周期的G1、S和G2期。与细胞周期相关的主要观察到的变化是核大小以及黑白染色质团块和点的数量持续增加。通过多变量数据分析实现了92.5%的总体正确分类。然而，注意到ALL病例之间存在显著差异。
