Guze L B, Montgomerie J Z, Harwick H J, Kalmanson G M
Invest Urol. 1976 Jul;14(1):13-5.
A study has been done of immunization against Streptococcus faecalis pyelonephritis in the rat. Intravenous, subcutaneous, and bladder immunizations were tested with intravenous and retrograde challenge. Logarithmic and stationary growth phase organisms were used separately for both immunization and challenge. The only instance of significant, but incomplete, protection was in animals immunized subcutaneously or intravenously and challenged intravenously with log phase organisms. No correlation was found between circulating antibody response and infection. Serum bactericidal activity was not increased by immunization or infection.
一项关于大鼠粪肠球菌肾盂肾炎免疫接种的研究已经完成。分别采用静脉内、皮下和膀胱接种，并进行静脉内和逆行攻击试验。对数生长期和稳定生长期的细菌分别用于免疫接种和攻击试验。唯一显著但不完全的保护情况是在皮下或静脉内接种并以对数期细菌进行静脉内攻击的动物中。未发现循环抗体反应与感染之间存在相关性。免疫接种或感染均未增加血清杀菌活性。
