Ehret G, Jürgens A, Koch M
Abteilung Vergleichende Neurobiologie, Universität Ulm, Germany.
Neuroreport. 1993 Sep 10;4(11):1247-50. doi: 10.1097/00001756-199309000-00009.
Paternal behaviour (pup-searching and retrieving of pups) was studied in male house mice with different experience in pup care and oestrogen receptor immunoreactive (ER-IR) cells were localized and quantified in their brains. Experience with pups induced paternal behaviour and correlated with (a) the occurrence of ER-IR cells in the bed nucleus of the stria terminalis, hippocampus, subiculum, lateral septal nuclei, entorhinal and piriform cortex, (b) increased numbers of ER-IR cells in the medial preoptic area and arcuate nucleus of the hypothalamus, and (c) decreased presence of ER-IR cells in the periventricular grey of the midbrain. The data indicate oestrogen receptor modulation in the male brain and suggest that oestrogen binding in distinct brain areas is involved in the regulation of paternal behaviour.
对具有不同育幼经验的雄性家鼠的父性行为（搜寻幼崽和找回幼崽）进行了研究，并对其大脑中的雌激素受体免疫反应性（ER-IR）细胞进行了定位和定量分析。育幼经验诱导了父性行为，且与以下方面相关：（a）终纹床核、海马体、下托、外侧隔核、内嗅皮层和梨状皮层中ER-IR细胞的出现；（b）下丘脑视前内侧区和弓状核中ER-IR细胞数量的增加；（c）中脑脑室周围灰质中ER-IR细胞数量的减少。这些数据表明雄性大脑中雌激素受体的调节作用，并提示不同脑区的雌激素结合参与了父性行为的调节。
