Chukwuma C, Tuomilehto J
Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland.
J Diabetes Complications. 1993 Oct-Dec;7(4):250-62.
Diabetes is an important risk factor for the development of ischemic cerebrovascular disease or stroke. Diabetic patients are more susceptible to atherothromboembolic brain infarction and its consequent mortality than nondiabetic patients. Cerebrovascular disease in the diabetic population somewhat follows the same pattern as in the nondiabetic population, however, with greater severity in outcome for the former. The etiopathogenetic mechanisms of strokes and transient ischemic attacks in diabetic patients are apparently due to cerebral hemodynamic and vascular derangements, hyperglycemia, and other related risk factors. There is a great disparity in the wider information on coronary heart disease and stroke than on diabetes and stroke. A better understanding is required for the determinants of stroke and diabetes, and the epidemiology and pathophysiology of specific risk factors in different racial groups. There is a similarity in the evaluation, assessment, and management of diabetic and nondiabetic patients.
糖尿病是缺血性脑血管疾病或中风发生的重要危险因素。与非糖尿病患者相比，糖尿病患者更容易发生动脉粥样血栓栓塞性脑梗死及其导致的死亡。然而，糖尿病患者群体中的脑血管疾病在某种程度上与非糖尿病患者群体遵循相同的模式，只是前者的结局更为严重。糖尿病患者中风和短暂性脑缺血发作的病因发病机制显然是由于脑血流动力学和血管紊乱、高血糖以及其他相关危险因素。关于冠心病和中风的信息比关于糖尿病和中风的信息存在更大差异。需要更好地了解中风和糖尿病的决定因素，以及不同种族群体中特定危险因素的流行病学和病理生理学。糖尿病患者和非糖尿病患者在评估、评价和管理方面存在相似之处。
