[Effects of jiang tang tong mai ning on serum ascorbyl radical, superoxide dismutase activity, lipid peroxide level and tissue free oxygen radical in diabetic rats].

The effect of Jiang Tang Tong Mai Ning treatment on body weight, the level of blood sugar, the serum ascorbyl radical, SOD activity, LPO level and peroxidic radial (O2.-) of heart and kidney tissue in alloxan induced diabetic rats were observed. The results were also compared with that of Jiang Tang Jia Pian and vitamin E treated groups, which showed that the level of blood sugar, the level of serum ascorbyl radical, the concentration of LPO and peroxidic radical (O2.-) of myocardium and kidney tissue decreased significantly respectively (P < 0.01, 0.01, 0.01, 0.05), and the body weight, SOD activity increased obviously after the treatment (P < 0.05). For the first time, a W-wave between S-peak and T-peak of ESR spectrum in the tissue of rat, which is similar to the form of Fe-Mo-flavoprotein has been observed in this investigation, a positive correlation appears to exist between A value and the corresponding G value of W-wave.