Aozasa K, Mishima K, Ohsawa M
Department of Pathology, Nara Medical University, Japan.
Leuk Lymphoma. 1993 Jul;10(4-5):353-7. doi: 10.3109/10428199309148560.
Clinical and pathologic features of 69 cases with primary hepatic lymphoma, 52 reported from Western countries and 17 cases from Japan, were summarized in terms of clinical findings including age and sex, past history, presenting symptoms, and physical findings, diagnostic procedures including imaging techniques and histopathology, and finally therapy and follow-up. The present cases included four patients with an acquired immunodeficiency syndrome and 12 with a history of chronic liver diseases. Histologically, all cases were non-Hodgkin's lymphoma with diffuse large cell type being the most common immunochemically about 80% were B-cell type. Follow-up showed that hepatic lymphoma had a relatively favourable prognosis provided early detection was possible.
总结了69例原发性肝淋巴瘤患者的临床和病理特征，其中52例来自西方国家，17例来自日本，内容包括临床发现，如年龄、性别、既往史、症状表现及体格检查；诊断方法，包括影像学技术和组织病理学；最后是治疗及随访情况。这些病例包括4例获得性免疫缺陷综合征患者和12例有慢性肝病病史的患者。组织学上，所有病例均为非霍奇金淋巴瘤，弥漫大细胞型最为常见，免疫化学检查显示约80%为B细胞型。随访表明，如果能早期发现，肝淋巴瘤预后相对较好。
