Takenobu A, Okamoto H, Hirao J, Kurosaki M, Watanabe T, Hori T, Ohama E
Department of Neurosurgery, Tottori University School of Medicine.
Noshuyo Byori. 1993;10(2):125-30.
A 20-year-old female with von Recklinghausen's disease became aware of hoarseness and dysphagia with a right neck mass, and received subtotal resection of a jugular foramen neurofibroma. One year later the jugular foramen tumor recurred and pathologic examination at excision showed a malignant transformation. Despite postoperative chemotherapy and radiotherapy, it recurred soon and followed the metastatic cerebral tumor by meningeal dissemination. Malignant nerve sheath tumors of the jugular foramen are very rare and the clinical course and pathological pictures of this tumor are reviewed.
一名患有冯雷克林霍增氏病的20岁女性意识到声音嘶哑、吞咽困难并伴有右侧颈部肿块，接受了颈静脉孔神经纤维瘤次全切除术。一年后，颈静脉孔肿瘤复发，切除时的病理检查显示发生了恶性转化。尽管术后进行了化疗和放疗，但肿瘤很快复发，并通过脑膜播散出现了脑转移瘤。颈静脉孔恶性神经鞘瘤非常罕见，本文对该肿瘤的临床病程和病理图像进行了综述。
