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Sequence of an exon of the feline p53 gene--mutation in a lymphosarcoma.

作者信息

Mayr B, Heczko U, Schellander K, Schleger W, Reifinger M

机构信息

Institute for Animal Breeding and Genetics, Veterinary University, Vienna, Austria.

出版信息

Br Vet J. 1993 Jul-Aug;149(4):387-90. doi: 10.1016/S0007-1935(05)80077-6.

DOI:10.1016/S0007-1935(05)80077-6
PMID:8221043
Abstract

Exon 8 of tumour suppressor gene p53 was sequenced in domestic cats and showed remarkable similarity to the human sequence. Only four of the 13 nucleotide differences gave rise to interspecific amino acid differences. In an investigated lymphosarcoma we detected a mutation cgg --> tgg (arginine --> tryptophan) in codon no. 282.

摘要

相似文献

1
Sequence of an exon of the feline p53 gene--mutation in a lymphosarcoma.
Br Vet J. 1993 Jul-Aug;149(4):387-90. doi: 10.1016/S0007-1935(05)80077-6.
2
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Novel p53 tumour suppressor mutations in cases of spindle cell sarcoma, pleomorphic sarcoma and fibrosarcoma in cats.猫的梭形细胞肉瘤、多形性肉瘤和纤维肉瘤病例中的新型p53肿瘤抑制基因突变。
Vet Res Commun. 1998 Jun;22(4):249-55. doi: 10.1023/a:1006091215330.